National Dengue Control Unit (NDCU) was established in 2005 as a decision taken by the Ministry of Health following a major DF/DHF outbreak occurred in 2004. It is responsible for the coordination of control and preventive activities related to dengue at central level between different stakeholders
Former National coordinators/Directors
| Dr. Lakshmi De Silva | 2005 - 2008 |
| Dr. Lakmini Magodarathna | 2008-2009 |
| Dr. N. Pannila Hetti | 2009 – 2011 |
| Dr. R. Batuwantudawe | 2011 - 2013 |
| Dr. U. Ranasignhe | 2013 |
| Dr. Hasitha A. Tissera | 2013 – 2015 |
| Dr. A.R.M. Thowfeek | 2015 – 2017 |
| Dr. Hasitha A. Tissera | 2017 – 2019 |
| Dr. Aruna Jayasekera | 2019 - 2021 |
| Dr. Sudath Samaraweera | 2021 to date |